The molecular basis of disorders of red cell enzymes
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چکیده
منابع مشابه
The molecular basis of disorders of red cell enzymes.
The mature red cell has no nucleus or organelles and therefore cannot synthesise protein or lipids. It is totally dependent on glycolysis to convert glucose into an energy source. Glucose is phosphorylated by hexokinase to glucose-6-phosphate. This is the substrate for anaerobic glycolysis which proceeds through the Embden-Meyerhof pathway to pyruvate with production of ATP (fig 1). Some of the...
متن کاملLeader The molecular basis of disorders of red cell enzymes
The mature red cell has no nucleus or organelles and therefore cannot synthesise protein or lipids. It is totally dependent on glycolysis to convert glucose into an energy source. Glucose is phosphorylated by hexokinase to glucose-6-phosphate. This is the substrate for anaerobic glycolysis which proceeds through the Embden-Meyerhof pathway to pyruvate with production of ATP (fig 1). Some of the...
متن کاملThe molecular basis of disorders of the red cell membrane.
Haemolytic anaemia denotes a state in which there is an increased rate of red cell destruction. It can be classified on the basis of whether the defect is intrinsic to the red cell or extrinsic to the red cell (that is, a problem in the surrounding environment). Intrinsic defects include defects in the red cell membrane, defects in the red cell enzymes, and defects in globin structure and synth...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1999
ISSN: 0021-9746
DOI: 10.1136/jcp.52.4.241